Scientific Research An Academic Publisher. Prevalence estimates using the census. Archives of Neurology, 60,
Tuesday, October 15, 2019 10:26:16 PM Sex starving cartoon couples making hot silver cartoon picture Golden Age of Porn
An important pathological feature of Alzheimer's disease AD is the presence of extracellular senile plaques in the brain. Significant efforts have gone into understanding the mechanisms underlying the genes tied to FAD as the clinicopathological features are indistinguishable from regular onset AD. AD is characterized in patients by an inexorably progressing dementia. In vulnerable brain regions, such as the hippocampus and cortex, there is an accumulation of extracellular neuritic plaques and intracellular neurofibrillary tangles.❿
Image Source ⇑
Its primary function is not known, though it has been implicated as a regulator of synapse formation,  neural plasticity  and iron export. APP is an ancient and highly conserved protein. A number of distinct, largely independently- folding structural domains have been identified in the APP sequence.